Current treatment options in secondary renal hyperparathyroidism

Current treatment options in secondary hyperparathyroidism.

Renal secondary hyperparathyroidism in dogs.

The parathyroid glands secrete parathyroid hormone (PTH), which is important for maintaining calcium homeostasis. Parathyroid gland hyperplasia and subsequent hyperparathyroidism can occur secondary to chronic renal failure in dogs, resulting in significant alterations in calcium metabolism. Renal secondary hyperparathyroidism is a complex, multifactorial syndrome that involves changes in circu...

Secondary hyperparathyroidism in chronic renal disease - etiopathogenesis, diagnosis and treatment.

Chronic renal failure (CRF) is usually slowly progressive and irreversible impairment of the functional unit of the kidney – the nephron. According to the agreed and established criteria (National Kidney Foundation / Kidney Disease Outcomes Quality Initiative – NKF / KDOQI) there is a five-stage classification, so that in I stage glomerular filtration rate (GFR) > 90 mL/min/1.73m and morphologi...

Total parathyroidectomy in treatment of secondary (renal) hyperparathyroidism.

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Role of surgery in the treatment of renal secondary hyperparathyroidism.

It is generally considered that nearly all patients with chronic renal disease develop secondary hyperparathyroidism (sHPT). However, data on the exact prevalence are lacking. In the past 20 years, therapy for sHPT has been influenced profoundly by the introduction of new options for medical treatment. Medication with oral calcitriol and vitamin D analogues as well as calcimimetics led to a dec...